Clinical profile and outcome of children admitted with infective endocarditic at Tikur Anbessa Specialized Hospital

Authors

  • Selamawit Asmelash. MD
  • Etsegenet Gedlu, MD

Abstract

Background: Infective endocarditis (IE) is an infection of the endocardial surface of the heart. Infective endocarditis is associated with substantial morbidity and mortality. The diagnosis of IE is based upon a careful history and physical examination, blood culture and
laboratory results, an electrocardiogram, a chest radiograph, and an echocardiogram. Several sets of criteria for IE have been described. The most commonly accepted are the Duke criteria.
Objective: To study clinical features and etiologic agents, treatment and mortality of children admitted in the hospital with infective endocarditis. To study the predisposing or risk factor and isolated organism in blood culture for infective endocarditis.
Methodology: A retrospective analysis was conducted on the hospital medical records of pediatric patients under 15 years with the discharge diagnosis of IE who were admitted to Tikur Anbessa Specialized hospital between September 2005 and August 2009
Result: There were 66 episodes of infective endocarditis 20/63 (32%) were male and 43/63(68%) were female. The ages ranged from 4 to 168 months. Thirty eight (60.3%) of them had underlying chronic rheumatic valvular heart disease and 24(38.1%) had Congenital heart disease. Clinical presentations included: fever, pallor, congestive heart failure, Splenomegaly, clubbing, renal complication and neurological findings. Laboratory findings include: A haematocrit of less than 10mg/dl, Leukocytosis >12,000, Erythrocyte
sedimentation rate >30mm/hr s, hematuria, blood culture was positive only in 18 episodes of IE (27.3%). Coagulase negative staphylococcus aureus and staphylococcus aureus were the two most commonly isolated bacteria...

Downloads

Published

2010-05-25

How to Cite

Asmelash. MD, S. ., & Gedlu, MD, E. . (2010). Clinical profile and outcome of children admitted with infective endocarditic at Tikur Anbessa Specialized Hospital. Ethiopian Journal of Pediatrics and Child Health, 6(1). Retrieved from https://ejpch.net/index.php/ejpch/article/view/52