OUTCOME OF CHILDREN WITH ACUTE POST STREPTOCOCCAL GLOMERULONEPHRITIS IN TIKUR ANBESSA SPECIALIZED TEACHING HOSPITAL Addis Ababa, Ethiopia.

Abstract

Background: post streptococcal glomerulonephritis is one of the commonest causes of glomerular disease in developing countries. It is also one of the commonest causes of morbidity and in few cases mortality if proper identification and supportive treatment is not delivered.
Objective: the objective of this study is to look into the outcome and identify the predictors of outcomes of patients with post streptococcal glomerulonephritis in a tertiary care hospital. Materials and methods: Retrospective analysis of admissions of post streptococcal glomerulonephritis was conducted at Tikur Anbessa Specialized Teaching Hospital in Addis Ababa over eight year’s period from 2003 to 2010. Data was collected from patient records. The record of each patient was examined for the following information: age, sex, and address sociodemographic characteristics, predictors of outcome and complications of APSGN.
Results: there were 68 children with APSGN enrolled during the study period. 40 (58.8%) were males and 28 (41.2%) were females. The common age group of presentation was between 6 and 10years (30/68, 44.1%) followed by 3 and 5years (21/68, 30.9%). The age range was between 2.5-14years with a mean age of 7.5years.Two patients had unusual age of presentation one at 2years and 6 months and the other at 2yrs and 11months. 44 (64.7%) had sore throat or skin infection before presentation while 24(35.3%) did not give any history of infection before presentation.
Fifty two (76.5%) patients were from Addis Ababa and 14 patients presented from Oromia region around Addis Ababa while 2 patients came from remote areas Thirty two (47.1%) patients had follow up at the renal clinic for a duration,of 6 months - 1
year while the remaining were followed for less than 6 months and were released from follow up when they were stabilized.
Conclusion: There was no significant association between age, sex, renal dysfunction and severity of hypertension to the outcome of patients and .there was no complication observed during the follow up period.