CRIGLER NAJJAR SYNDROME TYPE I, A RARE BUT SEVERE CAUSE OF UNCONJUGATED HYPERBILIRUBINEMIA IN CHILDREN

Abstract

Crigler Najjar Syndrome Type I is a rare and severe autosomal recessive disorder of bilirubin metabolism. It has been associated with consanguinity in some patients. Infants without any evidence of hemolysis, develop severe, permanent, unconjugated hyperbilirubinemia within the first few days of life resulting in chronic kernicterus